Optimal control analysis for modeling HIV transmission

Document Type : Research Article

Author

• K. R. Cheneke

Department of Mathematics, Wollega University, Nekemte, Ethiopia.

10.22067/ijnao.2023.78096.1165

Abstract

In this study, a modified model of HIV with therapeutic and preventive controls is developed. Moreover, a simple evaluation of the optimal control problem is investigated. We construct the Hamiltonian function by way of integrating Pontryagin’s maximal principle to achieve the point-wise optimal solution. The effects obtained from the version analysis strengthen public health education to a conscious population, PrEP for early activation of HIV infection prevention, and early treatment with artwork for safe life after HIV infection. Moreover, numerical simulations are done using the MATLAB platform to illustrate the qualitative conduct of the HIV infection. In the end, we receive that adhering to ART protective prone people, the usage of PrEP along with different prevention control is safer control measures.

Keywords

• HIV
• Optimal control problem
• Basic reproduction number, Numerical simulation

Main Subjects

• Numerical methods for differential equations and its applications

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